IBI has published or featured a number of studies and reports on mental health and work outcomes such as absence and job performance. We have highlighted ways that employers can support early and effective treatment for depression and comorbid conditions. We examined the effects of interventions that target work-related stress, such as cognitive-behavioral interventions and work time control. In addition, we have conducted research on the relationship between workplace climate, stress, and use of sick days. This article brings together insights from our own and others’ research on workforce mental health and work outcomes.